Journal Cover Articles

Selected Publications

  • [12] Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a neurogenic niche
    Yuanyuan Zheng, Xufeng Xue, Agnes M. Resto Irizarry, Zida Li, Yue Shao, Yi Zheng, Gang Zhao, and Jianping Fu
    Science Advances, vol. 5, eaax5933, 2019.
    DOI: 10.1126/sciadv.aax5933. PMCID: PubMed - in process.
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  • [11] Controlled modeling of human epiblast and amnion development using stem cells
    Yi Zheng, Xufeng Xue, Yue Shao, Sicong Wang, Sajedeh Nasr Esfahani, Zida Li, Jonathon M. Muncie, Johnathon N. Lakins, Valerie M. Weaver, Deborah L. Gumucio, and Jianping Fu
    Nature, vol. 573, pp. 421-425, 2019.
    DOI: 10.1038/s41586-019-1535-2. PMCID: PubMed - in process.
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    Commentary by Amander T. Clark, Nature, vol. 573, pp. 350-351, 2019. [PDF]
    Highlighted by Nature News, "Embryo-like structures created from human stem cells". (link)
    Highlighted by Nature Podcast, "Modelling early embryos". (link)
    Highlighted by National Public Radio (NPR) News, "Scientists create a device that can mass-produce human embryoids". (link)
    Highlighted by BBC News, "Embryoids from stem cells". (link)
    Highlighted by MIT Technology Review, "Meet the 'artificial embryos' being called uncanny and spectacular". (link)
    Highlighted by Chemical & Engineering News (C&EN), "Microfluidic device brews human embryo-like structures". (link)
  • [10] Debate ethics of embryo models from stem cells
    Nicolas Rivron, Martin Pera, Janet Rossant, Alfonso Martinez Arias, Magdalena Zernicka-Goetz, Jianping Fu, Suzanne van den Brink, Annelien Bredenoord, Wybo Dondorp, Guido de Wert, Insoo Hyun, Megan Munsie, and Rosario Isasi
    Nature, vol. 564, pp. 183-185, 2018.
    DOI: 10.1038/d41586-018-07663-9. PMCID: PubMed - in process.
    | PDF | PubMed
  • [9] Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells
    Xufeng Xue, Yubing Sun, Agnes M. Resto-Irizarry, Ye Yuan, Koh Meng Aw Yong, Yi Zheng, Shinuo Weng, Yue Shao, Yimin Chai, Lorenz Studer, and Jianping Fu
    Nature Materials, vol. 17, pp. 633-641, 2018.
    DOI: 10.1038/s41563-018-0082-9.
    | PDF | Supplemental Materials | PubMed

    Commentary by Mukul Tewary and Peter W. Zandstra, Nature Materials, vol. 17, pp. 571-572, 2017. [PDF]
  • [8] A pluripotent stem cell-based model for post-implantation human amniotic sac development
    Yue Shao, Kenichiro Taniguchi, Ryan F. Townshend, Toshio Miki, Deborah L. Gumucio, and Jianping Fu
    Nature Communications, vol. 8, 208, 2017.
    DOI: 10.1038/s41467-017-00236-w. PMCID: PMC5547056.
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    Access the recommendation on F1000Prime
    Recommended in F1000Prime by Magdalena Zernicka-Goetz. [PDF]
    Highlighted by MIT Technology Review, "Artificial human embryos are coming, and no one knows how to handle them". (link)
  • [7] Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche
    Yue Shao, Kenichiro Taniguchi, Katherine Gurdziel, Ryan F. Townshend, Xufeng Xue, Koh Meng Aw Yong, Jianming Sang, Jason R. Spence, Deborah L. Gumucio, and Jianping Fu
    Nature Materials, vol. 16, pp. 419-425, 2017.
    DOI: 10.1038/nmat4829. PMCID: PMC5374007.
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    Commentary by Martin Pera, Nature Materials, vol. 16, pp. 394-395, 2017. [PDF]
  • [6] Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis
    Shinuo Weng, Yue Shao, Weiqiang Chen, and Jianping Fu
    Nature Materials, vol. 15, pp. 961-967, 2016.
    DOI: 10.1038/nmat4654. PMCID: PMC4996707.
    | PDF | Supplemental Materials | PubMed
  • [5] Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells
    Yubing Sun, Koh Meng Aw Yong, Luis G. Villa-Diaz, Xiaoli Zhang, Weiqiang Chen, Renee Philson, Shinuo Weng, Haoxing Xu, Paul H. Krebsbach, and Jianping Fu
    Nature Materials, vol. 13, pp. 599-604, 2014.
    DOI: 10.1038/nmat3945. PMCID: PMC4051885.
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    Commentary by Emily Rhodes Lowry & Christopher E. Henderson, Nature Materials, vol. 13, pp. 543-544, 2014. [PDF]
    Commentary by Ning Wang, Cell Stem Cell, vol. 14, pp. 701-703, 2014. [PDF]
  • [4] Adhesive signature-based, label-free isolation of human pluripotent stem cells
    Ankur Singh, Shalu Suri, Ted T. Lee, Jamie M. Chilton, Marissa T. Cooke, Weiqiang Chen, Jianping Fu, Steven L. Stice, Hang Lu, Todd C. McDevitt, and Andrés J. García
    Nature Methods, vol. 10, pp. 438-444, 2013.
    DOI: 10.1038/nmeth.2437. PMCID: PMC3641175.
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    Commentary by Oscar J. Abilez & Joseph C. Wu, Nature Materials, vol. 12, pp. 474-476, 2013; web link.
  • [3] Mechanical regulation of cell function with geometrically modulated elastomeric substrates
    Jianping Fu, Yang-Kao Wang, Michael T. Yang, Ravi A. Desai, Xiang Yu, Zhijun Liu, and Christopher S. Chen
    Nature Methods, vol. 7, pp. 733-736, 2010.
    DOI: 10.1038/nmeth.1487.  PMCID: PMC3069358.
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    Commentary by Amnon Buxboim & Dennis Discher, Nature Methods, vol. 7, pp. 695-697, 2010. [PDF]
  • [2] A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and protein
    Jianping Fu, Reto B. Schoch, Anna L. Stevens, Steven R. Tannenbaum, and Jongyoon Han
    Nature Nanotechnology, vol. 2, pp. 121-128, 2007.
    DOI: 10.1038/nnano.2006.206.  PMCID: PMC2621439.
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    Commentary by Robert Austin, Nature Nanotechnology, vol. 2, pp. 121-128, 2007. [PDF]
  • [1] Molecular sieving in periodic free-energy landscapes created by patterned nanofilter arrays
    Jianping Fu, Juhwan Yoo, and Jongyoon Han
    Physical Review Letters, vol. 97, 018103, 2006.
    DOI: 10.1103/PhysRevLett.97.018103.  PMCID: PMC1752241.
    | PDF | PubMed

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